Unpacking Ketamine: The Science Behind Its Antidepressant Effects

Dive into the fascinating world of ketamine, where we explore its two enantiomers, S (+) and R (−), and their unique effects on depression treatment. Discover the recent FDA approval of S (+) ketamine as a nasal antidepressant and the various administration routes used by practitioners. We'll break down the pharmacokinetics and discuss the ongoing debates surrounding its mechanism of action, including its impact on NMDA receptors and neurotransmitter systems. Join us as we unravel the complexities and controversies of this groundbreaking therapy!